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IG2) TAE: NR SAE: NR Ascertainment of outcomes assessed: questionnaires Author Funding N; study design; eligibility Participants characteristics Diagnosis details Intervention Outcomes Guo (2006) 124 Funding source: Eli Lilly and Company N screened = 399 N randomized = 367 IG1, n = 125 IG2, n = 120 CG, n = 122 ITT analysis used for primary outcome: yes Inclusion: men 18 or older in monogamous relationship, at least 3 mo hx of ED, with Psychogenic, organic or mixed cause Exclusion: hx of radical prostatectomy; or other pelvic surgery with subsequent failure to achieve erection; renal insufficiency, hepatobiliary disease, unstable angina within the last 6 mo; hx of MI; coronary artery bypass graft surgery, or precutaneous coronary intervention within 90 d prior to 1st visit; hx of HIV infection; tx with nitrates, cancer chemotherapy, or antiandrogens (discretionary criteria was ineffective tx with sildenafil) Age, mean (range): 52 (2482) y Race: East| South-eastern 100% Co-morbidities, n (%): hypertension 77 (21); DM 42 (11 . 103 In another trial,163 there was a statistically significant higher median (percentile range 1090) IIEF score in the tadalafil group in comparison with the vardenafil group: 30 (2530) versus 28 (23 . 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